BD 222361 - Difco H. influenzae Type B Antiserum, 1mL High-Specificity Reagent for Haemophilus Identification,EA
The BD 222361 Difco H. influenzae Type B Antiserum is a high-quality diagnostic reagent designed to aid in the rapid and accurate identification of Haemophilus influenzae type b (Hib). This antiserum provides strong, type-specific agglutination, enabling clear differentiation of Hib from other Haemophilus species and serotypes. Supplied in a 1mL vial, the reagent is ready for use in slide agglutination tests, supporting microbiology laboratories in confirming clinically significant Hib isolates associated with meningitis, epiglottitis, bacteremia, pneumonia, and other invasive infections.
Key Benefits
The BD Difco H. influenzae Type B Antiserum delivers rapid, dependable agglutination results with high sensitivity and specificity. Its precise formulation ensures consistent reactions that support accurate organism classification. This single-use diagnostic tool helps streamline workflows and reduces interpretation errors by providing clear visual endpoints. Manufactured with BDs stringent quality controls, the antiserum offers reproducibility essential for both routine clinical testing and epidemiological investigations.
Compatibility and Applications
This antiserum is compatible with standard slide agglutination procedures and is commonly used for:
- Confirming Hib isolates from blood, CSF, and respiratory cultures
- Differentiating Hib from other H. influenzae serotypes
- Supporting outbreak investigations and surveillance programs
- Advanced research involving encapsulated Haemophilus organisms
The antiserum is suitable for use in hospital microbiology labs, public health laboratories, academic research centers, and reference facilities performing serological identification of fastidious organisms.
Usage Guidelines
Follow standard slide agglutination procedures. Place a small amount of a well-isolated organism suspension onto a clean glass slide and add a drop of BD 222361 antiserum. Gently mix and observe for visible agglutination within the recommended timeframe. Always compare reactions with appropriate positive and negative controls. Do not use the reagent if turbidity, contamination, or deterioration is noted. Store the vial refrigerated at 28C and avoid repeated freeze-thaw cycles.
Certifications, Safety Standards, and Regulatory Approvals
The BD 222361 Difco H. influenzae Type B Antiserum is manufactured under ISO 9001 and ISO 13485 certified quality systems for in vitro diagnostic reagents. It complies with FDA and CE regulatory requirements for IVD use and undergoes rigorous quality testing for sterility, specificity, and consistent performance. Each lot is validated using known Hib control strains.
Comparison with Competitor Products
Compared to generic antisera, BD Difco reagents provide superior clarity of agglutination, reduced background noise, and highly reproducible serotyping performance. Competitor antisera may show weak or variable reactions, leading to ambiguous serotype interpretation. BDs controlled production and standardized potency ensure reliable Hib detection across all laboratory environments.
Typical User Profile and Application Scenarios
This antiserum is typically used by clinical microbiologists, public health analysts, infectious disease researchers, and diagnostic technologists. It is ideal for:
- Confirmatory Hib identification in clinical isolates
- Pediatric infectious disease diagnostics
- Serotyping during epidemiological surveillance
- Research focused on encapsulated bacterial pathogens
Best Practices for Use and Maintenance
Use aseptic technique when handling both the reagent and the organism suspension. Allow the antiserum to reach room temperature before testing to prevent condensation. Always include controls for verification. Avoid drying out the slide during interpretation, and discard used slides and culture materials in biohazard containers. Keep the reagent tightly capped and return it to refrigeration immediately after use.
Regulatory and Safety Information
This product is intended for in vitro diagnostic use only and should be handled by trained laboratory personnel. Cultures tested with this reagent may contain pathogenic organisms; therefore, biosafety level 2 precautions are required. Wear gloves, protective eyewear, and laboratory coats. Dispose of microbiological waste according to institutional and regulatory guidelines.
How to Order
To order the BD 222361 Difco H. influenzae Type B Antiserum (1mL), add the product to your cart and complete the purchase through CIA Medicals secure checkout. For bulk inquiries, standing orders, or additional product documentation, contact CIA Medical customer service at (312) 275-5850 or submit a request using the contact form on this page. Our team is ready to support your laboratorys serotyping needs.
