BD 230886 - Sensi-Disc Novobiocin 5 g, Antibiotic Susceptibility Testing Discs for Microbiological Applications, EA
The BD 230886 - BD Sensi-Disc Novobiocin 5 g is a precision-manufactured antibiotic susceptibility testing disc used in the Kirby-Bauer disk diffusion method to determine bacterial sensitivity to novobiocin. Manufactured by Becton Dickinson (BD) under the Sensi-Disc brand, these high-quality, pre-impregnated filter paper discs are designed for consistent antibiotic diffusion and reproducible inhibition zone diameters in clinical and research microbiology laboratories.
Novobiocin, a broad-spectrum antibiotic that interferes with bacterial DNA gyrase activity, is primarily used in laboratory identification of Staphylococcus saprophyticuswhich is resistant to novobiocindistinguishing it from other coagulase-negative staphylococci that are typically sensitive. BD Sensi-Discs provide accurate, standardized, and dependable performance for routine antimicrobial susceptibility testing.
| Manufacturer | Application | Storage Requirements |
| 230886 | Antimicrobial Susceptibility Testing Disc | Requires Refrigeration |
Key Benefits
The BD Sensi-Disc Novobiocin 5 g offers numerous advantages for microbiology professionals:
- Precision and consistency: Delivers highly reproducible inhibition zones due to uniform antibiotic distribution.
- Reliable differentiation: Aids in accurate identification of Staphylococcus saprophyticus based on novobiocin resistance.
- Quality-assured manufacturing: Produced under stringent controls ensuring lot-to-lot consistency and compliance with CLSI and EUCAST guidelines.
- Convenient format: Ready-to-use discs eliminate preparation time and reduce handling errors.
- Stable antibiotic potency: Individually packaged and sealed to preserve potency and ensure reliable diffusion during testing.
Compatibility and Applications
The BD 230886 Sensi-Disc Novobiocin 5 g is compatible with standardized antimicrobial susceptibility testing methods, including those defined by CLSI and EUCAST. It is used for:
- Identification of Staphylococcus saprophyticus in urinary isolates based on novobiocin resistance.
- Routine antimicrobial susceptibility testing (AST) of Gram-positive bacteria.
- Clinical diagnostic laboratories performing differentiation of coagulase-negative staphylococcal species.
- Educational and research laboratories studying bacterial resistance patterns.
These discs are compatible with BD Mueller-Hinton Agar plates and other validated AST media formulations for optimal zone measurement accuracy.
Usage Guidelines
To perform susceptibility testing, inoculate the surface of a Mueller-Hinton agar plate with a standardized bacterial suspension (0.5 McFarland). Place one BD Sensi-Disc Novobiocin 5 g on the agar surface using sterile forceps or a disc dispenser, ensuring firm contact. Incubate the plate at 35 2C for 1618 hours in ambient air. After incubation, measure the diameter of the inhibition zone around the disc in millimeters.
- Interpretation (for Staphylococcus species):
- Zone = 16 mm: Resistant (indicative of S. saprophyticus).
- Zone = 17 mm: Sensitive.
Follow current CLSI M100 or EUCAST breakpoint guidelines for updated interpretive criteria. Always include quality control strains (e.g., Staphylococcus aureus ATCC 25923) to ensure test reliability.
Certifications, Safety Standards, and Regulatory Approvals
The BD Sensi-Disc Novobiocin 5 g complies with FDA, CE, and ISO 13485:2016 quality standards for in vitro diagnostic (IVD) use. BDs production process ensures uniform antibiotic concentration and diffusion performance as validated through batch testing using reference control organisms. Each lot is tested for potency, stability, and accuracy according to CLSI standards. The discs are also manufactured under GMP conditions, ensuring sterility and performance consistency across all global laboratories.
Comparison with Competitor Products
Compared to generic antibiotic discs, BD Sensi-Discs provide superior reproducibility, longer shelf life, and greater precision in antibiotic diffusion. While competitor discs may show variability in drug loading or inconsistent diffusion, BDs proprietary manufacturing process guarantees exact drug impregnation per disc and uniform paper density. This ensures reliable and accurate susceptibility readings essential for clinical diagnostics and regulatory compliance.
Typical User Profile and Application Scenarios
This product is designed for clinical microbiologists, diagnostic technicians, and researchers performing antimicrobial susceptibility testing or bacterial species differentiation. Typical scenarios include:
- Clinical laboratories conducting urinary tract infection (UTI) diagnostics.
- Microbiology labs identifying Staphylococcus species in culture isolates.
- Teaching laboratories demonstrating antimicrobial resistance mechanisms.
- Public health laboratories monitoring antibiotic resistance trends.
It is particularly valuable in confirming novobiocin resistance for Staphylococcus saprophyticus identification from urine cultures.
Best Practices for Use and Maintenance
Store BD Sensi-Discs at 28C in their original sealed container, protected from moisture and light. Remove only the number of discs required for immediate testing. Avoid excessive exposure to ambient conditions, which may reduce potency. Do not use expired discs. Handle using sterile forceps or an automatic dispenser to prevent contamination. Dispose of all used discs and plates according to institutional biosafety and clinical waste protocols.
Regulatory and Safety Information
The BD 230886 - BD Sensi-Disc Novobiocin 5 g is classified as an FDA-cleared and CE-marked in vitro diagnostic product for professional laboratory use. It is non-toxic, non-pyrogenic, and free from latex and DEHP. A Safety Data Sheet (SDS) is available from BD upon request, detailing safe handling and disposal procedures. The discs are intended solely for use by trained laboratory personnel in accordance with CLSI M2-A13 standards for antimicrobial susceptibility testing.
How to Order
To order the BD 230886 - BD Sensi-Disc Novobiocin 5 g, add the product to your cart and complete checkout through CIA Medical. We offer competitive pricing, fast shipping, and technical support for hospitals, research institutions, and diagnostic laboratories. For bulk purchases, Certificates of Analysis, or product documentation, contact CIA Medicals customer service team at (312) 275-5850 or use the contact form on this page. Our representatives are available to assist with product specifications, performance validation, and lot certification inquiries.
