BD 231591 - Disk Susceptibility Sensi-Disc Cefoxitin 30mcg Reliable AST Disk for Detecting Beta-Lactam Resistance, 10/PK
The BD 231591 Disk Susceptibility Sensi-Disc Cefoxitin 30mcg is a high-precision antimicrobial susceptibility testing (AST) reagent designed to evaluate bacterial sensitivity to cefoxitin, a cephamycin antibiotic used as a surrogate marker for methicillin resistance in Staphylococcus aureus and coagulase-negative staphylococci. Each sterile paper disk contains 30 micrograms of cefoxitin, providing a consistent diffusion gradient for accurate susceptibility interpretation using the Kirby-Bauer disk diffusion method. Manufactured under BDs rigorous quality standards, this Sensi-Disc ensures reliable, reproducible results essential for guiding clinical decisions and antimicrobial stewardship.
| Manufacturer | Application | Storage Requirements |
| 231591 | Antimicrobial Susceptibility Testing Disc | Requires Refrigeration |
Key Benefits
The BD 231591 Cefoxitin 30mcg Sensi-Disc offers reliable potency, uniform diffusion, and clear inhibition zone formation. Cefoxitin is the preferred disk for detecting mecA-mediated methicillin resistance, making this product critical for accurate MRSA and MRSE identification. The sterile, single-use format reduces contamination risk, supports consistent performance, and enhances workflow efficiency in clinical microbiology laboratories. BDs precise formulation ensures dependable results across high-volume AST workflows.
Compatibility and Applications
This Sensi-Disc is compatible with Mueller-Hinton agar and follows CLSI and EUCAST guidelines for disk diffusion AST. It is commonly used for testing:
- Staphylococcus aureus (MRSA screening)
- Coagulase-negative staphylococci
- Enterobacterales (where cephamycin activity assessment is required)
- Gram-negative organisms involved in hospital-acquired infections
Cefoxitin testing is especially valuable in detecting methicillin resistance, cephamycin resistance, and beta-lactamase production patterns.
Usage Guidelines
Prepare a bacterial suspension equivalent to a 0.5 McFarland standard and evenly inoculate a Mueller-Hinton agar plate. Using sterile forceps or a disk dispenser, place the BD 231591 Cefoxitin 30mcg disk onto the agar surface. Incubate plates at 35C for 1618 hours following current CLSI or EUCAST recommendations. Measure inhibition zone diameters and interpret results according to the latest breakpoints. Store disks at 28C in sealed containers with desiccants to maintain potency.
Certifications, Safety Standards, and Regulatory Approvals
The BD 231591 Sensi-Disc is produced in ISO 9001 and ISO 13485 certified facilities and complies with FDA and CE regulations for in vitro diagnostic (IVD) use. Each lot undergoes extensive quality testing for antibiotic potency, diffusion uniformity, sterility, and stability. BDs adherence to CLSI M100 performance standards ensures accurate and reproducible susceptibility results.
Comparison with Competitor Products
BD Sensi-Discs are recognized for superior consistency, potency retention, and manufacturing precision. Competitor products may show variations in antibiotic loading or inconsistent diffusion patterns, potentially leading to unreliable MRSA detection. Cefoxitin is especially sensitive to potency variations, and BDs stable formulation ensures clear, reproducible results every time.
Typical User Profile and Application Scenarios
This product is commonly used by clinical microbiologists, diagnostic technologists, infectious disease specialists, and research scientists. It is ideal for:
- MRSA/MRSE screening programs
- Routine AST in hospital and reference laboratories
- Resistance surveillance and epidemiological studies
- Research on beta-lactam and cephamycin resistance mechanisms
Best Practices for Use and Maintenance
Handle disks with sterile forceps and avoid touching the antibiotic surface. Allow refrigerated disks to reach room temperature before opening the container to prevent condensation. Verify performance with recommended QC organisms, such as Staphylococcus aureus ATCC 25923 and Staphylococcus aureus ATCC 43300 (MRSA control). Store disks properly and do not use expired or moisture-compromised disks. Dispose of used disks and plates following institutional biohazard protocols.
Regulatory and Safety Information
The BD 231591 Cefoxitin 30mcg disk is intended for in vitro diagnostic use by trained laboratory personnel. All procedures involving clinical isolates must follow biosafety level 2 guidelines. Use appropriate PPEincluding gloves, lab coats, and protective eyewearand dispose of all biological waste in compliance with regulatory and institutional standards.
How to Order
To order the BD 231591 Disk Susceptibility Sensi-Disc Cefoxitin 30mcg, add the item to your cart and proceed through CIA Medicals secure checkout process. For bulk purchasing, laboratory supply contracts, or technical inquiries, contact CIA Medical customer service at (312) 275-5850 or use the inquiry form on this page. Our team can assist with product availability, documentation, and pricing.
