BD 231644 - Disk Susceptibility Sensi-Disc Imipenem IPM-10 10mcg Accurate Antimicrobial Sensitivity Testing for Gram-Negative Bacteria,EA
The BD 231644 Disk Susceptibility Sensi-Disc Imipenem IPM-10 10mcg is a high-precision antibiotic susceptibility testing reagent used for determining bacterial resistance patterns to imipenem, a broad-spectrum carbapenem antibiotic. Each sterile paper disk contains 10 micrograms of imipenem and is designed for use in standardized disk diffusion testing, such as the Kirby-Bauer method. Manufactured under BDs stringent quality controls, these disks provide consistent, reproducible results to support accurate antimicrobial resistance (AMR) surveillance and clinical decision-making in microbiology laboratories.
| Manufacturer | Application | Storage Requirements |
| 231644 | Antimicrobial Susceptibility Testing Disc | Requires Refrigeration |
Key Benefits
The BD 231644 Imipenem 10mcg Sensi-Disc ensures highly reliable, reproducible, and standardized antimicrobial sensitivity testing. Each disk is impregnated with a precisely measured dose of imipenem, ensuring consistent diffusion and zone formation across test plates. The sterile, ready-to-use format reduces contamination risks and simplifies laboratory workflow. By providing accurate and consistent susceptibility data, these disks enable clinicians to make evidence-based decisions, optimizing antibiotic therapy and improving patient outcomes while supporting antimicrobial stewardship initiatives.
Compatibility and Applications
The BD 231644 Sensi-Disc is compatible with standard Mueller-Hinton agar and designed for use in accordance with CLSI (Clinical and Laboratory Standards Institute) and EUCAST (European Committee on Antimicrobial Susceptibility Testing) guidelines. It is used to evaluate bacterial susceptibility, particularly among Gram-negative organisms such as Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Enterobacter species. The imipenem 10mcg disk is ideal for hospital diagnostic microbiology labs, public health laboratories, and research institutions monitoring carbapenem-resistant Enterobacteriaceae (CRE) and other multidrug-resistant pathogens.
Usage Guidelines
To use the BD 231644 Imipenem Sensi-Disc, prepare a standardized bacterial suspension and inoculate evenly over a Mueller-Hinton agar plate. Using sterile forceps or a disk dispenser, place the imipenem 10mcg disk onto the inoculated surface and incubate at 3537C for 1618 hours. Measure the diameter of the inhibition zone in millimeters and interpret the results using CLSI or EUCAST interpretive standards. Store disks at 28C in a dry, dark place and allow them to reach room temperature before opening to avoid condensation, which may affect potency.
Certifications, Safety Standards, and Regulatory Approvals
The BD 231644 Imipenem IPM-10 Sensi-Disc is manufactured under ISO 9001 and ISO 13485 certified quality systems, ensuring compliance with FDA and CE regulatory requirements for in vitro diagnostic products. Each batch undergoes rigorous quality control testing to verify antibiotic potency, diffusion consistency, and sterility. The disks conform to CLSI performance specifications, ensuring laboratory confidence in test reliability and result reproducibility.
Comparison with Competitor Products
Compared to generic antibiotic disks, BDs Sensi-Disc line is renowned for its superior uniformity and stability. Competitor brands often show inconsistencies in antibiotic concentration or diffusion rates, leading to unreliable results. BDs proprietary manufacturing process ensures even impregnation and precise antibiotic dosing, producing consistent inhibition zones across multiple tests. Additionally, BDs moisture-resistant packaging extends product shelf life and preserves antibiotic activity, ensuring high-quality performance even under demanding laboratory conditions.
Typical User Profile and Application Scenarios
The BD 231644 Imipenem 10mcg Sensi-Disc is primarily used by clinical microbiologists, laboratory technologists, and infection control specialists. It is commonly utilized in hospitals, public health laboratories, and academic institutions to identify resistant bacterial strains, guide antibiotic selection, and support antimicrobial resistance surveillance programs. It is particularly valuable in detecting carbapenem resistance among Gram-negative pathogens and assessing treatment options in critical care and infectious disease units.
Best Practices for Use and Maintenance
Handle disks using sterile tools and aseptic technique to prevent contamination. Avoid exposure to humidity and direct light, and keep the container tightly closed when not in use. Allow refrigerated disks to equilibrate to room temperature before opening to avoid condensation-related degradation. Always use appropriate control strains such as E. coli ATCC 25922 or Pseudomonas aeruginosa ATCC 27853 to validate test accuracy. Dispose of all used materials following institutional biohazard waste procedures.
Regulatory and Safety Information
The BD 231644 Imipenem 10mcg Sensi-Disc is intended for in vitro diagnostic use by trained laboratory professionals. It meets all applicable FDA, CE, and ISO regulatory standards. Although the disks are non-toxic, they should be handled using standard biosafety practices, including wearing gloves, lab coats, and eye protection when working with potentially infectious bacterial cultures. Used test materials must be autoclaved or disinfected before disposal.
How to Order
To order the BD 231644 Disk Susceptibility Sensi-Disc Imipenem IPM-10 10mcg, add the product to your cart and proceed through CIA Medicals secure checkout process. For bulk orders, institutional supply agreements, or technical support, contact CIA Medical customer service at (312) 275-5850 or submit your inquiry via the contact form on this page. Our team can assist with pricing, availability, and technical documentation to ensure seamless integration into your laboratorys antimicrobial testing protocols.
