BD 231692 - Sensi-Disc Piperacillin/Tazobactam 100/10g Antimicrobial Susceptibility Testing Disc for Broad-Spectrum Beta-Lactamase Detection, 10/BX
The BD 231692 Sensi-Disc Piperacillin/Tazobactam 100/10g is a high-precision antimicrobial susceptibility testing (AST) disc designed for use in standardized Kirby-Bauer disk diffusion assays. Manufactured by BD (Becton Dickinson), a global leader in microbiological diagnostics, this disc contains 100 micrograms of piperacillin and 10 micrograms of tazobactam. The synergistic combination allows accurate evaluation of bacterial susceptibility to piperacillin/tazobactam, a broad-spectrum -lactam/-lactamase inhibitor antibiotic used in treating a wide range of Gram-negative and Gram-positive infections. The BD Sensi-Disc line ensures exceptional reliability, reproducibility, and compliance with CLSI and EUCAST standards for antibiotic susceptibility testing.
| Manufacturer | Application | Storage Requirements |
| 231692 | Antimicrobial Susceptibility Testing Disc | Requires Refrigeration |
Key Benefits
The BD Sensi-Disc Piperacillin/Tazobactam 100/10g provides precise and reproducible inhibition zones, ensuring accurate assessment of bacterial resistance mechanisms, including -lactamase production. Its exact antibiotic concentration allows for standardized results that support clinical decision-making. Packaged in moisture-controlled vials, these discs retain potency and performance integrity throughout their shelf life. BDs stringent manufacturing controls ensure uniform antibiotic distribution, consistent diffusion, and superior stability, enabling laboratories to maintain high-quality susceptibility testing workflows while supporting antimicrobial stewardship initiatives.
Compatibility and Applications
The BD 231692 Sensi-Disc is compatible with Mueller-Hinton Agar (MHA) and used in disk diffusion testing for a variety of bacterial isolates, including Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterobacter spp., and Proteus spp. It is particularly effective in identifying susceptibility to piperacillin/tazobactam combination therapy used in serious infections such as sepsis, pneumonia, intra-abdominal infections, and urinary tract infections. The product is routinely used in hospital diagnostic laboratories, pharmaceutical testing facilities, and public health institutions for antimicrobial resistance surveillance and therapy optimization.
Usage Guidelines
Prepare a standardized bacterial suspension equivalent to a 0.5 McFarland standard and evenly inoculate a Mueller-Hinton Agar plate. Using sterile forceps or an automated dispenser, apply the BD Piperacillin/Tazobactam 100/10g disc onto the agar surface. Incubate at 352C for 1618 hours in ambient air. Measure the inhibition zone diameter in millimeters and interpret according to CLSI or EUCAST breakpoints. Include control organisms such as Escherichia coli ATCC 25922 and Pseudomonas aeruginosa ATCC 27853 to validate testing accuracy. Avoid prolonged exposure of discs to air or humidity prior to use.
Certifications, Safety Standards, and Regulatory Approvals
The BD 231692 Sensi-Disc Piperacillin/Tazobactam 100/10g is manufactured under ISO 13485 and ISO 9001 certified quality systems and complies with FDA and CE requirements for in vitro diagnostic (IVD) devices. Production adheres to Good Manufacturing Practices (GMP) and validation according to CLSI M100 and ISO 20776-1 standards for antimicrobial susceptibility testing. Each lot undergoes comprehensive potency and diffusion validation to ensure uniformity and regulatory compliance. BDs globally recognized quality assurance guarantees consistent performance for clinical, research, and public health applications.
Comparison with Competitor Products
Compared to competitor susceptibility discs, BD Sensi-Discs demonstrate superior diffusion consistency, antibiotic stability, and lot-to-lot reproducibility. While lower-quality alternatives may show variable potency or diffusion rates, BDs proprietary manufacturing ensures each disc maintains accurate antibiotic release and uniform diffusion halos. The dual formulation of piperacillin with tazobactam effectively captures -lactamase-mediated resistance mechanisms, providing clearer, more clinically relevant interpretations. Laboratories worldwide rely on BD Sensi-Discs for precision and trust in antibiotic resistance testing.
Typical User Profile and Application Scenarios
This product is designed for clinical microbiologists, diagnostic technologists, and researchers performing antimicrobial susceptibility testing. It is commonly used in hospital microbiology laboratories, infection control units, academic research centers, and pharmaceutical quality control labs. The BD Piperacillin/Tazobactam 100/10g disc is essential for monitoring multidrug-resistant organisms (MDROs) and supporting targeted antibiotic therapy for critically ill patients.
Best Practices for Use and Maintenance
Store BD Sensi-Discs at 28C in their original sealed containers to maintain potency. Allow the container to reach room temperature (2025C) before opening to prevent moisture condensation. Handle discs with sterile forceps or automated dispensers under aseptic conditions. Always use fresh Mueller-Hinton Agar plates of uniform depth (approximately 4mm) and pH 7.27.4. Dispose of used discs and cultures as biohazardous waste in accordance with institutional biosafety procedures. Regularly verify disc potency using recommended control organisms to ensure reliable results.
Regulatory and Safety Information
This product is intended for professional laboratory use only. Handle bacterial cultures using Biosafety Level 2 (BSL-2) containment protocols. Always wear appropriate personal protective equipment (PPE), including gloves, lab coats, and protective eyewear. Avoid direct skin contact with antibiotic discs and bacterial suspensions. Dispose of all used materials following institutional biosafety and environmental safety regulations. Refer to the products Safety Data Sheet (SDS) for detailed handling, hazard, and storage information. BD ensures full compliance with global laboratory safety and environmental protection standards.
How to Order
To purchase the BD 231692 Sensi-Disc Piperacillin/Tazobactam 100/10g, add the product to your cart and complete the secure checkout process on the CIA Medical website. For institutional or bulk orders, contact CIA Medical customer service at (312) 275-5850 or submit an inquiry using the online form. CIA Medical provides competitive pricing, prompt delivery, and expert support for all BD Sensi-Disc antimicrobial susceptibility testing products.
