BD 231749 - DrySlide Nitrocefin Rapid Beta-Lactamase Detection Reagent for Microbiology Labs, 25/BX
The BD 231749 DrySlide Nitrocefin is a high-performance diagnostic reagent designed for rapid detection of beta-lactamase enzyme activity in bacteria. Manufactured by BD (Becton Dickinson), this reagent provides a reliable and efficient means for microbiology laboratories to identify antibiotic-resistant strains. Each DrySlide Nitrocefin is impregnated with a chromogenic cephalosporin substrate that changes color upon hydrolysis by beta-lactamase, delivering clear and rapid results within minutes. Its compact, ready-to-use format allows for easy testing without the need for complex preparation, making it ideal for routine antimicrobial susceptibility testing in clinical, veterinary, and research settings.
| Manufacturer | Application | Test Format |
| 231749 | Other Infectious Disease Test Kit | Slide Format |
Key Benefits
The BD DrySlide Nitrocefin offers a fast and accurate diagnostic solution, reducing the time required to detect resistance mechanisms in bacteria. Its colorimetric reaction simplifies interpretation, allowing healthcare professionals to visually confirm results without additional equipment. The products single-use format minimizes the risk of cross-contamination, ensuring high testing accuracy and consistency. Additionally, its stability and long shelf life enhance laboratory efficiency, reducing waste and operational costs. By supporting early detection of resistant pathogens, it ultimately contributes to improved patient outcomes and effective antimicrobial stewardship.
Compatibility and Applications
This reagent is compatible with a wide range of bacterial isolates and can be used alongside standard microbiological tools such as inoculating loops, culture plates, and antibiotic susceptibility discs. It is commonly employed in hospitals, diagnostic laboratories, and pharmaceutical research facilities for the identification of beta-lactamase-producing organisms including Staphylococcus aureus, Haemophilus influenzae, Neisseria gonorrhoeae, and Moraxella catarrhalis. The BD 231749 DrySlide Nitrocefin is also suitable for use in veterinary and environmental testing applications where rapid detection of resistant microorganisms is essential.
Usage Guidelines
To perform the test, apply a small amount of bacterial colony directly onto the DrySlide Nitrocefin surface using a sterile inoculating loop or applicator. Observe the color change within 15 minutes. A red color indicates a positive reaction (beta-lactamase present), while no color change indicates a negative result. The reagent should be stored in a cool, dry place and used before the expiration date printed on the packaging. Always follow laboratory biosafety procedures and dispose of used materials according to local regulations.
Certifications, Safety Standards, and Regulatory Approvals
The BD DrySlide Nitrocefin complies with international laboratory quality and safety standards. It is produced in accordance with ISO 13485 requirements for medical devices and adheres to Good Manufacturing Practices (GMP). The product has CE marking for in vitro diagnostic (IVD) use in the European market and meets FDA regulations for laboratory reagents. These certifications ensure consistent quality, performance reliability, and adherence to regulatory expectations for diagnostic reagents.
Comparison with Competitor Products
Compared to other chromogenic beta-lactamase detection reagents, the BD 231749 DrySlide Nitrocefin stands out for its superior stability, consistent color development, and minimal false positives. While competing products may require solution preparation or have shorter shelf lives, BDs dry format eliminates reagent handling and offers enhanced convenience. Laboratories favor BDs formulation for its dependable results, batch-to-batch consistency, and trusted global reputation in microbiological diagnostics. This makes it a preferred choice over alternatives from lesser-known suppliers or generic brands.
Typical User Profile and Application Scenarios
The BD 231749 DrySlide Nitrocefin is primarily used by clinical microbiologists, infection control specialists, and laboratory technicians who perform antimicrobial resistance testing. It is particularly valuable in hospital microbiology labs where rapid detection of resistant organisms supports timely infection management. It is also used in research institutions investigating mechanisms of antibiotic resistance and in veterinary labs testing bacterial isolates from animals. The products ease of use and reliability make it suitable for both high-throughput and small-scale testing environments.
Best Practices for Use and Maintenance
For best results, store the BD DrySlide Nitrocefin in its original packaging at recommended storage conditions and avoid exposure to light or moisture. Always use sterile tools to prevent contamination. Ensure that colonies are taken from fresh culture plates for accurate enzyme detection. Do not reuse or attempt to regenerate slides. After testing, discard all materials in compliance with biosafety waste management procedures. Regular verification with known beta-lactamase-positive and negative control strains is recommended to ensure ongoing test accuracy and reagent integrity.
Regulatory and Safety Information
This diagnostic reagent is intended for professional laboratory use only. It should not be used for direct patient diagnosis without appropriate confirmatory testing. Users should wear protective gloves and eyewear when handling the reagent and test samples. The products Material Safety Data Sheet (MSDS) provides detailed hazard and handling information and should be reviewed before use. The BD 231749 DrySlide Nitrocefin meets all applicable regulatory requirements for IVD laboratory reagents, ensuring full compliance with healthcare and safety standards.
How to Order
To purchase the BD 231749 DrySlide Nitrocefin, simply add the product to your cart and proceed through the secure checkout process on the CIA Medical website. For large-scale or recurring laboratory orders, customers can contact CIA Medical customer service at (312) 275-5850 or submit a bulk inquiry through the contact form available on the product page. CIA Medical provides fast shipping, transparent pricing, and reliable customer support for all BD laboratory and diagnostic products.
