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BD 231761 - Linezolid Sensi-Disc Precision 30mcg Disc for Oxazolidinone Antimicrobial Susceptibility Testing
The BD 231761 Linezolid Sensi-Disc is a high-performance antimicrobial susceptibility testing (AST) disc designed for evaluating bacterial sensitivity to linezolid, a key oxazolidinone antibiotic used for treating multidrug-resistant Gram-positive infections. Each sterile disc is formulated to deliver standardized antibiotic diffusion on Mueller-Hinton agar, producing accurate, reproducible inhibition zones in accordance with the Kirby-Bauer disk diffusion method. BDs precise manufacturing ensures dependable potency, diffusion uniformity, and clear interpretation across clinical laboratories.
| Manufacturer | Application | Storage Requirements |
| 231761 | Antimicrobial Susceptibility Testing Disc | Requires Refrigeration |
Key Benefits
This Linezolid Sensi-Disc offers excellent potency stability and generates sharp zone boundaries, enhancing interpretive accuracy for resistant pathogens such as MRSA, VRE, and other highly significant Gram-positive organisms. The single-use sterile disc format minimizes contamination risk, streamlines workflow, and ensures consistent antibiotic delivery. BDs tight lot-to-lot controls support reliable results essential for guiding treatment decisions in serious infections.
Compatibility and Applications
The BD 231761 Linezolid disc is designed for standard Mueller-Hinton agar and follows CLSI and EUCAST guidelines. It is commonly used for susceptibility testing of:
- Staphylococcus aureus (including MRSA)
- Staphylococcus epidermidis
- Enterococcus faecalis and E. faecium (including VRE)
- Streptococcus pneumoniae (with modified methods)
- Other Gram-positive cocci requiring oxazolidinone susceptibility assessment
Linezolid is a critical therapeutic option in severe skin, respiratory, bloodstream, and bone infections, making this disc vital in routine clinical testing.
Usage Guidelines
Prepare a 0.5 McFarland bacterial suspension and inoculate Mueller-Hinton agar plates evenly. Apply the BD 231761 disc using sterile forceps or a calibrated disc dispenser. Incubate plates at 3537C for 1620 hours. Measure inhibition zones and interpret according to the latest CLSI or EUCAST breakpoints. Store discs at 28C and protect from moisture using sealed, desiccated packaging.
Certifications, Safety Standards, and Regulatory Approvals
This Sensi-Disc is produced in ISO 9001 and ISO 13485 certified facilities and adheres to FDA and CE regulatory requirements for in vitro diagnostic (IVD) materials. Each lot is tested for potency accuracy, diffusion uniformity, sterility, and long-term stability to ensure high-quality results.
Comparison with Competitor Products
BD Linezolid Sensi-Discs offer superior potency retention, consistent antibiotic distribution, and more reliable zone clarity compared with many generic discs. Competing brands may suffer from moisture absorption, variable antibiotic loading, or inconsistent diffusionfactors that compromise AST accuracy. BDs stringent quality controls ensure dependable performance, especially important for organisms with emerging resistance patterns.
Typical User Profile and Application Scenarios
This product is widely used by:
- Clinical microbiologists in hospital and reference laboratories
- Infectious disease diagnostic units
- Public health surveillance labs monitoring linezolid resistance
- Research institutions studying Gram-positive resistance mechanisms
Best Practices for Use and Maintenance
Allow discs to reach room temperature before opening to prevent condensation. Handle only with sterile forceps and minimize exposure to ambient humidity. Use validated QC strains such as Staphylococcus aureus ATCC 25923 and Enterococcus faecalis ATCC 29212 to confirm system performance. Dispose of used discs and plates according to institutional biohazard waste guidelines.
Regulatory and Safety Information
The BD 231761 Sensi-Disc Linezolid is intended for in vitro diagnostic use by trained laboratory personnel. Follow biosafety level 2 precautions when handling clinical isolates. Use appropriate PPE and dispose of all contaminated materials following regulatory and institutional safety standards.
How to Order
To order the BD 231761 Linezolid Sensi-Disc, add the product to your cart and proceed through CIA Medicals secure checkout system. For bulk orders, ongoing supply contracts, or technical assistance, contact CIA Medical customer service at (312) 275-5850 or use the inquiry form on this page. Our team is available to support your laboratorys testing needs.
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