BD 240658 - BBL Rabbit Plasma Reagent Test Qualitative/Differential 10 x 3mL Lyophilized For Staphylococcus Coagulase Testing
The BD 240658 BBL Rabbit Plasma Reagent Test is a high-quality, lyophilized reagent used for the qualitative and differential detection of coagulase production by Staphylococcus species, particularly Staphylococcus aureus. Manufactured by BD (Becton Dickinson), this diagnostic reagent provides rapid and reliable differentiation between coagulase-positive and coagulase-negative staphylococci. Each box contains 10 vials of 3mL lyophilized rabbit plasma, ready for reconstitution prior to use. The test plays a vital role in clinical microbiology for identifying pathogenic S. aureus strains associated with skin infections, pneumonia, sepsis, and other serious infections.
| Manufacturer | 240658 |
| Application | Microbiology Reagent |
| Chemical Name | Rabbit Coagulase Plasma with Citrate |
| For Use With | For Direct Tube Method |
| Form | Lyophilized |
| Type | Bacterial Identification |
Key Benefits
The BD BBL Rabbit Plasma Reagent ensures high sensitivity and specificity for coagulase detection. Its lyophilized form guarantees long shelf life and consistent reactivity after reconstitution. The reagent provides visible clot formation in positive reactions, enabling straightforward interpretation without specialized equipment. Compared to conventional methods, this BD formulation minimizes false negatives and supports rapid organism differentiation, improving workflow efficiency in diagnostic laboratories. Each batch undergoes stringent quality control testing to ensure reproducibility, purity, and performance across all test lots.
Compatibility and Applications
This reagent is designed for use in the tube coagulase test for identifying Staphylococcus aureus. It can be used with pure bacterial isolates grown on standard media such as blood agar or tryptic soy agar. The BD 240658 reagent is suitable for clinical, veterinary, and research laboratories. Typical applications include confirming S. aureus from wound swabs, blood cultures, or other clinical specimens, as well as differentiating coagulase-negative staphylococci such as S. epidermidis and S. saprophyticus. The reagent may also be used in teaching and training settings for microbiology students learning bacterial identification techniques.
Usage Guidelines
Reconstitute each 3mL vial of BD BBL Rabbit Plasma Reagent by adding 3mL of sterile distilled water. Mix gently to dissolve completely without creating foam. For testing, emulsify a loopful of a pure Staphylococcus colony in 0.5mL of the reconstituted plasma. Incubate at 3537C and observe for clot formation at 1, 2, and 4 hours; confirm results at 24 hours if necessary. A firm clot that remains in place when the tube is tilted indicates a positive coagulase reaction. If no clot forms, the isolate is coagulase-negative. Always include known positive and negative control strains (e.g., S. aureus ATCC 25923 and S. epidermidis ATCC 12228) to validate test performance.
Certifications, Safety Standards, and Regulatory Approvals
The BD 240658 Rabbit Plasma Reagent is produced under ISO 13485-certified quality management systems and meets FDA and CE requirements for in vitro diagnostic (IVD) use. It is manufactured following Good Manufacturing Practices (GMP) to ensure product sterility, purity, and batch consistency. Each lot is performance-tested against reference strains as defined by CLSI standards to guarantee diagnostic accuracy and regulatory compliance for clinical laboratory use.
Comparison with Competitor Products
Compared to other rabbit plasma coagulase reagents, BDs BBL formulation provides superior clarity, stability, and reliability. Many competitor reagents may show variable clotting activity after reconstitution or shorter shelf life. BDs lyophilized preparation maintains consistent reactivity, minimizing reagent waste and ensuring dependable results across multiple tests. Its well-established global use in hospital and reference laboratories underscores BDs leadership in coagulase testing solutions.
Typical User Profile and Application Scenarios
The BD 240658 BBL Rabbit Plasma Reagent is used by clinical microbiologists, diagnostic technologists, and laboratory professionals in hospitals, public health labs, and veterinary diagnostic centers. It is particularly valuable in laboratories performing routine bacterial identification and antimicrobial susceptibility testing. The product is also used in microbiology training programs for demonstrating classical biochemical reactions and differentiating Staphylococcus species based on enzyme activity.
Best Practices for Use and Maintenance
Store unopened lyophilized vials at 28C in a dry environment. Once reconstituted, refrigerate the plasma reagent and use within the recommended stability period (usually 7 days). Avoid repeated freeze-thaw cycles or contamination. Always use aseptic techniques and sterile equipment when preparing or handling the reagent. Dispose of all used materials in accordance with biohazard waste disposal regulations. Perform regular quality control using reference strains to confirm reagent performance and ensure test reliability.
Regulatory and Safety Information
This product is intended for professional laboratory use only and should be handled by trained personnel. Use appropriate personal protective equipment (PPE) such as gloves and lab coats when handling reagents and bacterial cultures. Treat all specimens and used reagents as potentially infectious and dispose of them by autoclaving or incineration. Refer to the Safety Data Sheet (SDS) and product insert for detailed information on handling, precautions, and hazard identification. BD guarantees full compliance with international standards for diagnostic reagent safety and performance.
How to Order
To order the BD 240658 BBL Rabbit Plasma Reagent Test Qualitative/Differential (10 x 3mL Lyophilized for Staphylococcus), add the product to your cart and proceed through CIA Medicals secure checkout. For large-volume or institutional orders, contact CIA Medical customer service at (312) 275-5850 or submit an inquiry through the online form. CIA Medical offers competitive pricing, fast delivery, and dedicated support for all BD BBL diagnostic reagents and microbiological testing products.
