BD 274449 - BBL Macro-Vue #104 Syphilis RPR Card Direct Testing 300 Count Bx
The BD 274449 BBL Macro-Vue #104 Syphilis RPR Card Test is a high-quality, rapid serological diagnostic kit used for the qualitative and quantitative detection of reagin antibodies associated with syphilis infection. Manufactured by BD (Becton Dickinson), this trusted 300-count box provides a reliable, easy-to-use method for screening serum or plasma samples directly. The test employs the Rapid Plasma Reagin (RPR) flocculation method using carbon particle antigen suspension to visualize antigen-antibody reactions. Each kit delivers consistent, accurate, and easy-to-interpret results for both clinical and public health laboratory use.
| Manufacturer | 274449 |
| Application | Sexual Health Test Kit |
| CLIA Classification | CLIA Non-Waived |
| Contents 1 | 20 Gauge Dispensing Needle, 3 mL Ampule Antigen, Antigen Dispensing Bottle Stirrers, (30) Cards With (10) 18 mm Circle Spots, (300) 0.05 mL Capillaries |
| Test Format | Test Card Format |
Key Benefits
The BD Macro-Vue #104 RPR Card Test offers rapid and dependable results, typically within 8 minutes, allowing clinicians to make timely diagnostic decisions. Its direct testing method eliminates the need for additional reagents, reducing handling time and minimizing the potential for error. The carbon-enhanced antigen provides a distinct black flocculation, making results easy to interpret without microscopy. With BDs proven manufacturing consistency, this test ensures high sensitivity, specificity, and reproducibility. The 300-test format supports efficient batch testing and cost-effective screening for healthcare facilities of all sizes.
Compatibility and Applications
The BD 274449 RPR Card Test is compatible with both serum and plasma specimens collected via standard phlebotomy techniques. It is widely used in hospitals, clinics, diagnostic laboratories, and public health programs for initial syphilis screening and disease monitoring. The test is also suitable for blood bank screening, antenatal checkups, and occupational health assessments. It can be used in conjunction with confirmatory treponemal tests such as FTA-ABS (Fluorescent Treponemal Antibody-Absorption) to establish a complete diagnostic profile for syphilis infection.
Usage Guidelines
Before testing, allow all reagents and samples to reach room temperature. Place one drop of patient serum or plasma onto a test circle on the RPR card. Add a drop of antigen suspension directly over the sample and rotate the card for 8 minutes at 100 rpm using a mechanical rotator. Observe the card visually for black flocculation against a white backgroundpresence of clumping indicates a reactive (positive) result. Record qualitative or quantitative titers as required. Dispose of all biological materials and used cards in accordance with biosafety protocols. Always follow the manufacturers instructions provided with the kit for precise procedures and quality assurance.
Certifications, Safety Standards, and Regulatory Approvals
The BD 274449 BBL Macro-Vue #104 Syphilis RPR Card Test complies with FDA 510(k) clearance for in vitro diagnostic (IVD) use and is CE-marked for global laboratory applications. It is produced in accordance with ISO 13485 standards and follows Good Manufacturing Practices (GMP). The kits reagents undergo strict quality control testing to ensure consistent performance and reagent stability throughout its shelf life. These certifications confirm BDs commitment to delivering safe, effective, and compliant diagnostic solutions trusted worldwide.
Comparison with Competitor Products
Compared to other syphilis RPR tests, BDs Macro-Vue #104 kit is recognized for its superior accuracy, reagent stability, and ease of use. Competitor kits may require additional reagents or exhibit variability in flocculation visibility. BDs advanced formulation ensures consistent carbon particle suspension, resulting in distinct and reliable results even in borderline samples. The ready-to-use reagents and durable packaging make BDs kit an industry standard in syphilis screening programs and clinical diagnostics, offering better workflow efficiency and reduced technician handling time.
Typical User Profile and Application Scenarios
This RPR test kit is ideal for use by laboratory technicians, clinical microbiologists, and public health professionals performing infectious disease screening. It is commonly applied in routine diagnostic testing for sexually transmitted infections (STIs), blood bank screening, and prenatal syphilis evaluations. Public health agencies and laboratories performing mass screening or epidemiological studies also rely on the BD 274449 RPR Card Test for its scalability, reliability, and ease of interpretation.
Best Practices for Use and Maintenance
Store the BD Macro-Vue #104 RPR Card Test kit at 28C in a dry environment, protected from light. Do not freeze reagents. Use sterile pipettes or droppers for sample handling to avoid contamination. Ensure that mechanical rotators are calibrated for accurate rotation speeds. Run known positive and negative controls daily to verify reagent integrity and procedural accuracy. Avoid using expired reagents or cards, as this may affect result reliability. Dispose of all biological materials according to institutional biosafety and infection control guidelines.
Regulatory and Safety Information
This product is intended for professional laboratory use only and must be handled by trained personnel using appropriate personal protective equipment (PPE). Although the reagents are non-infectious, universal precautions for handling human specimens should be observed. All waste must be sterilized or incinerated before disposal. Refer to the Safety Data Sheet (SDS) and package insert for comprehensive safety, handling, and storage information. BD ensures all RPR diagnostic kits meet international safety and environmental compliance requirements.
How to Order
To purchase the BD 274449 BBL Macro-Vue #104 Syphilis RPR Card Direct Testing 300 Count Box, add the product to your cart and complete the secure checkout process on the CIA Medical website. For high-volume orders or institutional supply agreements, contact CIA Medical customer service at (312) 275-5850 or submit a bulk inquiry through the contact form. CIA Medical provides prompt delivery, competitive pricing, and dedicated support for all BD diagnostic testing and infectious disease screening products.
