BD 230874 - Disk Susceptibility Sensi-Disc Nalidixic Acid 30mcg Reliable AST Disc for Gram-Negative Susceptibility Testing, 50/TB

BD 230874 - Disk Susceptibility Sensi-Disc Nalidixic Acid 30mcg Reliable AST Disc for Gram-Negative Susceptibility Testing, 50/TB

The BD 230874 Disk Susceptibility Sensi-Disc Nalidixic Acid 30mcg is a high-precision antimicrobial susceptibility testing (AST) disc formulated to evaluate bacterial sensitivity to nalidixic acid, a quinolone-class antibiotic widely used in laboratory identification workflows. Each sterile disc contains 30 micrograms of nalidixic acid and is engineered to deliver standardized antibiotic diffusion on Mueller-Hinton agar, ensuring accurate and reproducible inhibition zones for routine diagnostic and surveillance testing.

Key Benefits

This BD Sensi-Disc provides consistent potency and reliable diffusion patterns, enabling clear interpretation of susceptibility profiles in Gram-negative bacteria. Its sterile, single-use design minimizes contamination risks and supports high laboratory throughput. BDs rigorous quality control ensures uniform antibiotic loading and dependable zone clarity, helping clinicians detect resistance trends and guide antimicrobial therapy decisions.

Compatibility and Applications

The BD 230874 Nalidixic Acid 30mcg disc is compatible with standard Mueller-Hinton agar used in Kirby-Bauer disk diffusion testing. It is commonly used for:

• Screening quinolone susceptibility in Enterobacterales
• Identifying nalidixic acidresistant strains associated with fluoroquinolone resistance
• Routine AST workflows in clinical microbiology laboratories
• Research and surveillance of emerging bacterial resistance mechanisms

Target organisms include:

• Escherichia coli
• Klebsiella species
• Enterobacter species
• Other Gram-negative bacilli tested for quinolone activity

Usage Guidelines

Prepare a 0.5 McFarland standard bacterial suspension and evenly inoculate a Mueller-Hinton agar plate. Apply the BD 230874 disc using sterile forceps or an automated disc dispenser. Incubate at 3537C for 1620 hours. Measure the resulting inhibition zone and interpret results using current CLSI or EUCAST breakpoints. Store discs at 28C in sealed containers with desiccants to maintain potency.

Certifications, Safety Standards, and Regulatory Approvals

This Sensi-Disc is manufactured under ISO 9001 and ISO 13485 certified quality systems and meets FDA and CE regulatory requirements for in vitro diagnostic (IVD) AST materials. Each lot undergoes strict testing for antibiotic content, diffusion uniformity, sterility, and long-term stability.

Comparison with Competitor Products

BD Sensi-Discs are known for exceptional potency consistency and zone clarity, outperforming many generic susceptibility discs that may suffer from uneven antibiotic distribution or reduced stability. BDs tightly controlled manufacturing process ensures reliable results critical for antibiotic stewardship and diagnostic accuracy.

Typical User Profile and Application Scenarios

This AST disc is routinely used by:

• Clinical microbiologists in hospital and reference labs
• Infectious disease diagnostic teams
• Public health and epidemiology surveillance programs
• Academic and research laboratories studying quinolone resistance

Best Practices for Use and Maintenance

Allow discs to come to room temperature before opening to prevent condensation. Handle with sterile forceps only and avoid exposing discs to humidity. Confirm test accuracy using recommended QC strains such as E. coli ATCC 25922. Dispose of used discs and materials as regulated biohazard waste.

Regulatory and Safety Information

The BD 230874 Nalidixic Acid disc is intended for in vitro diagnostic use by trained laboratory personnel. Follow biosafety level 2 practices when handling clinical isolates. Use appropriate PPE and discard all contaminated materials per institutional and regulatory guidelines.

How to Order

To order the BD 230874 Disk Susceptibility Sensi-Disc Nalidixic Acid 30mcg, add the item to your cart and complete checkout through CIA Medicals secure ordering system. For bulk quantities, laboratory supply contracts, or product assistance, contact CIA Medical customer service at (312) 275-5850 or submit an inquiry through the form on this page. Our team is ready to help with availability, pricing, and technical documentation.