BD 231691 - Disk Susceptibility Sensi-Disc Piperacillin/Tazobactam 120mcg Reliable AST Disk for Broad-Spectrum Beta-Lactam/Beta-Lactamase Inhibitor Testing, EA
The BD 231691 Disk Susceptibility Sensi-Disc Piperacillin/Tazobactam 120mcg is a high-precision antimicrobial susceptibility testing (AST) reagent used to determine bacterial sensitivity to the combination therapy of piperacillin and tazobactam. Each sterile paper disk is impregnated with 100 micrograms of piperacillin and 10 micrograms of tazobactam (120 micrograms total), creating a standardized diffusion gradient for accurate susceptibility classification. Designed for use in disk diffusion assays such as the Kirby-Bauer method, these disks ensure consistent antibiotic distribution, reproducible inhibition zones, and dependable results for Gram-negative and select Gram-positive bacterial isolates.
| Manufacturer | Application | |
| 231691 | Antimicrobial Susceptibility Testing Disc |
Key Benefits
The BD 231691 Piperacillin/Tazobactam Sensi-Disc provides exceptional performance by delivering uniform antibiotic potency in every disk. Its combination of piperacillin with the beta-lactamase inhibitor tazobactam allows labs to identify resistance patterns more effectively than testing piperacillin alone. The sterile, single-use design reduces contamination risk and streamlines workflow. With BDs high manufacturing standards, laboratories can rely on consistent lot-to-lot reproducibility, enabling accurate resistance monitoring and optimal antimicrobial therapy selection.
Compatibility and Applications
BD Sensi-Discs are compatible with standard Mueller-Hinton agar and follow CLSI and EUCAST susceptibility testing standards. The BD 231691 disk is commonly used to test organisms such as Pseudomonas aeruginosa, Escherichia coli, Klebsiella pneumoniae, Enterobacter cloacae, and other clinically significant Gram-negative rods. These disks are essential in:
- Hospital microbiology laboratories
- Public health and antimicrobial surveillance programs
- Pharmaceutical and academic research
- Diagnostic workflows involving multidrug-resistant organisms
Usage Guidelines
Prepare a bacterial suspension adjusted to a 0.5 McFarland standard and inoculate a Mueller-Hinton agar plate uniformly. Using sterile forceps or a disk dispenser, place the BD 231691 Piperacillin/Tazobactam 120mcg disk on the agar surface. Incubate at 3537C for 1620 hours according to CLSI or EUCAST guidelines. Measure the inhibition zone diameter with a calibrated ruler or automated zone reader and interpret results against the latest clinical breakpoints. Store disks tightly sealed at 28C in a dry environment and let them equilibrate to room temperature before use.
Certifications, Safety Standards, and Regulatory Approvals
The BD 231691 Sensi-Disc is manufactured under ISO 9001 and ISO 13485 certified quality management systems. It meets FDA and CE regulatory requirements for in vitro diagnostic devices. Every lot is validated for potency, diffusion consistency, antibiotic stability, and sterility. BDs adherence to CLSI M100 guidelines ensures accurate, trusted susceptibility testing results that meet clinical laboratory standards.
Comparison with Competitor Products
BDs Sensi-Discs are widely recognized for superior reproducibility and potency retention compared to competitor AST disks. Inferior products often suffer from inconsistent antibiotic loading, uneven drug release, or suboptimal packaging that compromises disk stability. BD utilizes advanced impregnation and sealing processes to maintain antibiotic integrity and ensure uniform diffusion across all disks. This results in clearer zone edges and more reliable susceptibility classification.
Typical User Profile and Application Scenarios
This AST disk is used by clinical microbiologists, laboratory technologists, infection prevention teams, pharmaceutical researchers, and academic scientists. It is ideal for:
- Routine hospital susceptibility panels
- Confirming resistance in multidrug-resistant Gram-negative isolates
- Supporting antibiotic stewardship programs
- Research studies on beta-lactam/beta-lactamase inhibitor interactions
Best Practices for Use and Maintenance
Handle disks using sterile forceps or disk dispensers to prevent contamination. Store in original containers with desiccants to protect against humidity. Always verify performance with recommended quality control strains such as E. coli ATCC 25922 or Pseudomonas aeruginosa ATCC 27853. Avoid using expired disks, as diminished antibiotic activity may produce inaccurate zone sizes. Dispose of used materials as biohazard waste.
Regulatory and Safety Information
The BD 231691 Sensi-Disc Piperacillin/Tazobactam 120mcg is intended for in vitro diagnostic use only and should be handled by trained laboratory personnel. Testing should be conducted under biosafety level 2 conditions when working with clinical pathogens. Use PPE including gloves, lab coats, and protective eyewear. Dispose of cultured plates and disks in accordance with institutional and environmental regulations.
How to Order
To order the BD 231691 Disk Susceptibility Sensi-Disc Piperacillin/Tazobactam 120mcg, add the product to your cart and complete the purchase through CIA Medicals secure checkout. For bulk orders, clinical contracts, or technical questions, contact CIA Medical customer service at (312) 275-5850 or submit an inquiry through the contact form on this page. Our team is available to assist with availability, pricing, and product specifications.
